Biotechnology, MS

The Master of Science in Biotechnology is a Professional Master of Science (PSM) degree, an innovative graduate degree designed to allow students to pursue advanced training and excel in science while simultaneously developing highly valued business skills without acquiring a PhD or MBA. PSM programs are characterized by instruction in advanced science or mathematics, business courses, and a graduate co-op providing a real-world work experience. Graduates are referred to as “T-shaped” professionals with both deep knowledge of a specific discipline and broad knowledge of the communications and relational skills necessary to excel in any business and adapt to a changing workplace. The PSM is a nonthesis degree.

Molecular Biotechnology Concentration

The molecular biotechnology concentration provides students with didactic and practical knowledge in molecular biotechnology, protein expression, and structural biology. Students learn how to generate and optimize molecular forms used to express recombinant proteins to be used as biopharmaceuticals. Particular attention is paid to cutting-edge technologies such as RNAi and CRISPR/CAS9. In addition, the students learn how to purify biopharmaceuticals and analyze aggregation and how to prevent it.

Process Sciences Concentration

The process sciences concentration focuses on the production of drug substance of biopharmaceuticals from cell culture process to purification of the biologic molecules. The students learn the principles of development and implementation of biological manufacturing processes through the integration of concepts and fundamentals of engineering and life sciences. The concentration addresses biochemical engineering, mammalian cell culture process development, and protein purification. The learning of the students is reinforced by both lecture courses and project-driven laboratory experience that provides hands-on learning of cell culture and protein separation.

Biopharmaceutical Analytical Sciences Concentration

The biopharmaceutical analytical sciences concentration focuses on structures and activities of biological molecules and their variants formed during the production of biopharmaceuticals. Students learn the diversity of molecular forms derived from the biological products through various biological and chemical mechanisms and the impact of these structural changes on the safety and efficacy of these biopharmaceuticals. The students learn the science and practice applied in the biotechnology industry to analyze and characterize these molecular forms. This is accomplished through both lecture courses of the analytical sciences and project-driven laboratory experience that utilizes analytical techniques such as mass spectrometry and molecular separations.

Pharmaceutical Technologies Concentration

The pharmaceutical technologies concentration focuses on the conversion of purified proteins to biopharmaceutical drug products that are compatible for clinical use. This concentration addresses the design of the product formulation and the development and implementation of the drug product manufacturing processes. Students learn the sciences of the interactions of the biologic molecules in the process conditions and the relevant process technology, such as aseptic operations and freeze-drying, needed for drug product manufacturing. This is accomplished through both lecture courses and project-driven laboratory experience that offers hands-on learning of formulation design and drug product process development.

Biotechnology Enterprise Concentration

The biotechnology enterprise concentration integrates business and management skills with the science of biotechnology. Students learn the fundamental concepts of leadership, entrepreneurship and innovation, financial decision making, and marketing. They gain teamwork, management, and business development skills in the process and graduate prepared to become scientist-managers.

Complete all courses and requirements listed below unless otherwise indicated.

Core Requirements

General Core
BIOT 5120Introduction to Biotechnology3
BIOT 5219The Biotechnology Enterprise2
BIOT 5631Cell Culture Processes for Biopharmaceutical Production3
BIOL 6299Molecular Cell Biology for Biotechnology3
CHEM 5620Protein Chemistry3
CHEM 7317Analytical Biotechnology3
PHSC 6214Experimental Design and Biostatistics2
Co-op
BIOT 6500Professional Development for Co-op0
BIOT 6964Co-op Work Experience0

Concentrations

Complete one of the following five concentrations:

Biopharmaceutical Analytical Sciences Concentration

BIOT 5145Basic Biotechnology Lab Skills1
BIOT 7245Biotechnology Applications Laboratory3
CHEM 5550Introduction to Glycobiology and Glycoprotein Analysis3
CHEM 5616Protein Mass Spectrometry3
Electives5

Biotechnology Enterprise Concentration

BIOT 5225Managing and Leading a Biotechnology Company3
BIOT 5226Biotechnology Entrepreneurship3
BIOT 5227Economics and Marketing for Biotechnology Managers3
Electives6

Molecular Biotechnology Concentration

BIOT 5145Basic Biotechnology Lab Skills1
BIOT 5810Cutting-Edge Applications in Molecular Biotechnology3
BIOT 5850Higher-Order Structure Analytics3
BIOT 7245Biotechnology Applications Laboratory3
Electives5

Pharmaceutical Technologies Concentration

BIOT 5145Basic Biotechnology Lab Skills1
BIOT 5640Drug Product Processes for Biopharmaceuticals3
BIOT 5700Molecular Interactions of Proteins in Biopharmaceutical Formulations3
BIOT 7245Biotechnology Applications Laboratory3
Electives5

Process Sciences Concentration

BIOT 5145Basic Biotechnology Lab Skills1
BIOT 5560Bioprocess Fundamentals3
BIOT 5635Downstream Processes for Biopharmaceutical Production3
BIOT 7245Biotechnology Applications Laboratory3
Electives5

Elective List

Electives not on this list may be chosen with faculty advisor approval.
Bioinformatics Computational Methods 1
Biology Colloquium
Biological Electron Microscopy
Plant Biotechnology
Stem Cells and Regeneration
Microbial Biotechnology
Advanced Microbiology
Medical Microbiology
Biological Imaging
Immunology
Ethics in Biological Research
Dynamics of Microbial Ecology
Structural Biology
Research Problem Solving
Topics in Biochemistry Cell and Molecular Biology
Topics in Integrative Biology
The Role of Patents in the Biotechnology Industry, Past and Future
Managing and Leading a Biotechnology Company
Biotechnology Entrepreneurship
Economics and Marketing for Biotechnology Managers
Drug Safety and Immunogenicity
Bioprocess Fundamentals
Downstream Processes for Biopharmaceutical Production
Drug Product Processes for Biopharmaceuticals
Molecular Interactions of Proteins in Biopharmaceutical Formulations
Special Topics in Biotechnology
Special Topics in Biopharmaceutical Regulatory Science
Introduction to Glycobiology and Glycoprotein Analysis
Protein Mass Spectrometry
Protein Mass Spectrometry Laboratory
Principles of Chemical Biology for Chemists
Chemistry and Design of Protein Pharmaceuticals
Molecular Modeling
Chemical Kinetics
Principles and Analysis of Carbohydrates
Synthesis and Reactivity of Inorganic Compounds
Principles of Solid State Chemistry
Advances in Nanomaterials
Special Topics in Chemical Engineering
Chemical Engineering Kinetics
Enterprise Growth and Innovation
Managing Operations in Early Stage Ventures
Entrepreneurship: Services and Retail Business Creation
Business Planning for New Ventures
The American Healthcare System
Organizational Behavior, Work Flow Design, and Change Management
Law for Managers and Entrepreneurs
Information Analysis
Introduction to Nanomedicine Science and Technology
Nano- and Biomedical Commercialization: From Concept to Market
Introduction to Industry Research Guidelines
Research Skills and Ethics
Biomedical Chemical Analysis
The Chemistry and Biology of Drugs of Abuse
Behavioral Pharmacology and Drug Discovery
Imaging in Medicine and Drug Discovery
Biophysical Methods in Drug Discovery
Pharmaceutical Sciences Laboratory
Measuring and Managing the Cost of Production and Growth
Entrepreneurial Marketing and Selling
Lean Design and Development
Biochemical Toxicology Lab

Program Credit/GPA Requirements

34 total semester hours required
Minimum 3.000 GPA required