Biotechnology, MS

Northeastern’s Master of Science in Biotechnology is a professional master's program, an innovative, nonthesis graduate degree. It combines advanced interdisciplinary training in biotechnology, biology, chemistry, and pharmaceutical sciences with the development of high-value business skills critical to success in today’s dynamic workplace. Graduates are prepared to innovate, collaborate, and lead as research, managerial, or technical professionals in a wide range of biotechnology specialties.

Molecular Biotechnology Concentration

The molecular biotechnology concentration provides students with didactic and practical knowledge in molecular biotechnology, protein expression, and structural biology. Students learn how to generate and optimize molecular forms used to express recombinant proteins to be used as biopharmaceuticals. Particular attention is paid to cutting-edge technologies such as RNAi and CRISPR/CAS9. In addition, the students learn how to purify biopharmaceuticals and analyze aggregation and how to prevent it.

Process Sciences Concentration

The process sciences concentration focuses on the production of drug substance of biopharmaceuticals from cell culture process to purification of the biologic molecules. The students learn the principles of development and implementation of biological manufacturing processes through the integration of concepts and fundamentals of engineering and life sciences. The concentration addresses biochemical engineering, mammalian cell culture process development, and protein purification. The learning of the students is reinforced by both lecture courses and project-driven laboratory experience that provides hands-on learning of cell culture and protein separation.

Biopharmaceutical Analytical Sciences Concentration

The biopharmaceutical analytical sciences concentration focuses on structures and activities of biological molecules and their variants formed during the production of biopharmaceuticals. Students learn the diversity of molecular forms derived from the biological products through various biological and chemical mechanisms and the impact of these structural changes on the safety and efficacy of these biopharmaceuticals. The students learn the science and practice applied in the biotechnology industry to analyze and characterize these molecular forms. This is accomplished through both lecture courses of the analytical sciences and project-driven laboratory experience that utilizes analytical techniques such as mass spectrometry and molecular separations.

Pharmaceutical Technologies Concentration

The pharmaceutical technologies concentration focuses on the conversion of purified proteins to biopharmaceutical drug products that are compatible for clinical use. This concentration addresses the design of the product formulation and the development and implementation of the drug product manufacturing processes. Students learn the sciences of the interactions of the biologic molecules in the process conditions and the relevant process technology, such as aseptic operations and freeze-drying, needed for drug product manufacturing. This is accomplished through both lecture courses and project-driven laboratory experience that offers hands-on learning of formulation design and drug product process development.

Biotechnology Scientific Information Management Concentration

The scientific information management concentration focuses on the collection, analysis, and visualization of scientific data. This concentration addresses the issues surrounding big data that face industry today. Students have an opportunity to learn how to manage, store, visualize, and provide overall analysis of large scientific data sets. This is accomplished through both lecture courses and project-driven laboratory experience that provide hands-on learning of the impacts of data on the scientific process. 

Biotechnology Regulatory Science Concentration

The regulatory science concentration focuses on the science behind good regulatory practice today. This concentration addresses the issues surrounding current and innovative science practices that influence regulatory decisions. Students have an opportunity to learn the science behind compliance. This is accomplished through both lecture courses and project-driven laboratory experience that provides hands-on learning of the science behind dossier analysis.

Biotechnology Enterprise Concentration

The biotechnology enterprise concentration integrates business and management skills with the science of biotechnology. Students learn the fundamental concepts of leadership, entrepreneurship and innovation, financial decision making, and marketing. They gain teamwork, management, and business development skills in the process and graduate prepared to become scientist-managers.

Gordon Institute of Engineering Leadership

Master's Degree in Biotechnology with Graduate Certificate in Engineering Leadership

Students may complete a Master of Science in Biotechnology in addition to earning a Graduate Certificate in Engineering Leadership. Students must apply and be admitted to the Gordon Engineering Leadership Program in order to pursue this option. The certificate program requires fulfillment of the 16-semester-hour curriculum required to earn the Graduate Certificate in Engineering Leadership, which includes an industry-based challenge project with multiple mentors. The integrated 42-semester-hour master’s degree and certificate requires 26 hours of biotechnology course work. 

Engineering Leadership

Complete all courses and requirements listed below unless otherwise indicated.

Core Requirements

Required Core
BIOT 5120Introduction to Biotechnology3
BIOT 5219The Biotechnology Enterprise2
BIOT 5631Cell Culture Processes for Biopharmaceutical Production3
BIOT 6214Experimental Design and Biostatistics2
BIOL 6299Molecular Cell Biology for Biotechnology3
CHEM 5620Protein Chemistry3
CHEM 7317Analytical Biotechnology3
BIOT 6500Professional Development for Co-op0
BIOT 6964Co-op Work Experience0


Complete one of the following seven concentrations:

Molecular Biotechnology Concentration

BIOT 5145Basic Biotechnology Lab Skills1
BIOT 5810Cutting-Edge Applications in Molecular Biotechnology3
BIOT 5850Higher-Order Structure Analytics3
BIOT 7245Biotechnology Applications Laboratory3

Process Sciences Concentration

BIOT 5145Basic Biotechnology Lab Skills1
BIOT 5560Bioprocess Fundamentals3
BIOT 5635Downstream Processes for Biopharmaceutical Production3
BIOT 7245Biotechnology Applications Laboratory3

Biopharmaceutical Analytical Sciences Concentration

BIOT 5145Basic Biotechnology Lab Skills1
BIOT 7245Biotechnology Applications Laboratory3
CHEM 5550Introduction to Glycobiology and Glycoprotein Analysis3
CHEM 5616Protein Mass Spectrometry3

Pharmaceutical Technologies Concentration

BIOT 5145Basic Biotechnology Lab Skills1
BIOT 5640Drug Product Processes for Biopharmaceuticals3
BIOT 5700Molecular Interactions of Proteins in Biopharmaceutical Formulations3
BIOT 7245Biotechnology Applications Laboratory3

Scientific Information Management Concentration

BIOT 5145Basic Biotechnology Lab Skills1
BIOT 5400Scientific Information Management for Biotechnology Managers3
BIOT 7245Biotechnology Applications Laboratory3
DA 5020Collecting, Storing, and Retrieving Data4
or DA 5030 Introduction to Data Mining/Machine Learning
PPUA 5301Introduction to Computational Statistics4

Regulatory Science Concentration

BIOT 53303
BIOT 5340Introduction to Biotherapeutic Approvals3
BIOT 5500Introduction to Regulatory Science3
BIOT 7245Biotechnology Applications Laboratory3

Biotechnology Enterprise Concentration

BIOT 5225Managing and Leading a Biotechnology Company3
BIOT 5226Biotechnology Entrepreneurship3
BIOT 5227Economics and Marketing for Biotechnology Managers3

Elective List

Choose electives from the list and/or one-credit BUSN graduate level courses. Electives not on this list may be chosen with faculty advisor approval.
Bioinformatics Computational Methods 1
Biological Electron Microscopy
Plant Biotechnology
Stem Cells and Regeneration
Microbial Biotechnology
Advanced Microbiology
Medical Microbiology
Biological Imaging
Ethics in Biological Research
Dynamics of Microbial Ecology
The Role of Patents in the Biotechnology Industry, Past and Future
Managing and Leading a Biotechnology Company
Biotechnology Entrepreneurship
Economics and Marketing for Biotechnology Managers
Bioprocess Fundamentals
Downstream Processes for Biopharmaceutical Production
Drug Product Processes for Biopharmaceuticals
Molecular Interactions of Proteins in Biopharmaceutical Formulations
Introduction to Glycobiology and Glycoprotein Analysis
Protein Mass Spectrometry
Protein Mass Spectrometry Laboratory
Principles of Chemical Biology for Chemists
Chemistry and Design of Protein Pharmaceuticals
Molecular Modeling
Advances in Nanomaterials
Chemical Engineering Kinetics
Enterprise Growth and Innovation
Managing Operations in Early Stage Ventures
Entrepreneurship: Services and Retail Business Creation
Business Planning for New Ventures
The American Healthcare System
Organizational Behavior, Work Flow Design, and Change Management
Law for Managers and Entrepreneurs
Information Analysis
Introduction to Nanomedicine
Nano/Biomedical Commercialization: Concept to Market
Biomedical Chemical Analysis
Behavioral Pharmacology and Drug Discovery
Imaging in Medicine and Drug Discovery
Biophysical Methods in Drug Discovery
Pharmaceutical Sciences Laboratory
Entrepreneurial Marketing and Selling
Lean Design and Development

Program Credit/GPA Requirements

34 total semester hours required
Minimum 3.000 GPA required